منابع مشابه
Ultrastructural Morphology of Sperm from Human Globozoospermia
Globozoospermia is a rare disorder characterized by the presence of sperm with round head, lacking acrosome. Coiling tail around the nucleus has been reported since early human studies, but no specific significance has conferred it. By contrast, studies on animal models suggest that coiling tail around the nucleus could represent a crucial step of defective spermatogenesis, resulting in round-h...
متن کاملGlobozoospermia and lack of acrosome formation in GM130-deficient mice
Globozoospermia is a common reproductive disorder that causes male infertility in humans, and the malformation or loss of acrosomes is the prominent feature of this disease. Although the acrosome is thought to be derived from the Golgi apparatus, the detailed molecular mechanisms remain unclear. GM130 is a cis-side localized Golgi matrix protein,whereas the physiological functions of this prote...
متن کاملChromosome aneuploidy in the spermatozoa of two men with globozoospermia.
The objective of this study was to determine the aneuploidy level in spermatozoa in two men with globozoospermia. Sperm nuclei were analysed by fluorescence in-situ hybridization (FISH) in two infertile males with globozoospermia. Dual FISH for chromosomes 7 and 9, 13 and 21, and triple FISH for chromosomes X, Y, and 18 was performed. The main outcome measured was meiotic segregation difference...
متن کاملSperm parameters, protamine deficiency, and apoptosis in total globozoospermia
BACKGROUND Globozoospermia is a severe form of teratozoospermia (incidence < 0.1%) in infertile men that is characterized by round headed sperm and acrosomeless in semen. OBJECTIVE To compare the semen parameters, protamine deficiency, and apoptosis in ejaculated spermatozoa between globozoospermic and normozoospermic men. MATERIALS AND METHODS Thirty six semen samples were divided into two...
متن کاملCas Clinique / Case Report Globozoospermia Syndrome : Two Case
Globozoospermia syndrome is a rare teratozoospermia with an incidence below 0.1%. Presence of 100% round sperm heads, absence of acrosome, and messy sperm body and tail are the main characteristics of this syndrome. The activation ability of oocytes and consequently the fertilization rate decrease due to the absence of acrosome. The pathogenesis of this syndrome is not clear [1-2]. Globozoosper...
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ژورنال
عنوان ژورنال: International Journal of Infertility & Fetal Medicine
سال: 2014
ISSN: 2229-3817,2229-3833
DOI: 10.5005/jp-journals-10016-1077